Dr. Jonathan Sexton, Ph.D.
Assistant Professor, Internal Medicine, Division of Gastroenterology and Hepatology
Assistant Professor, College of Pharmacy, Medicinal Chemistry
Faculty Lead, Michigan Institute for Clinical & Health Research, MICHR, Drug Repurposing
Jonny Sexton has expertise in translational medicine, drug discovery and development with a specific focus on chronic liver diseases including non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD). He is also trained in quantitative biology, high-throughput screening, medicinal chemistry, big data mining and multivariate statistical analysis and animal models of diseases relating to diabetes and obesity. Jonny also engages in entrepreneurial activities and is the founder of Curl Bio LLC , a startup designed to perform drug development for NAFLD and NASH.
Jonny is the faculty lead of the center for drug repurposing at Michigan Institute for Clinical & Health Research (MICHR) and possesses a bioactive drug library of approximately 6,000 compounds. This center takes on a collaborative approach in drug repurposing and the service is available to all labs in the University of Michigan.
The Sexton lab has strong extramural funding in the form of continuous NIH funding in the areas of human metabolism, diabetes, metabolic syndrome & animal models of human diseases including an active R01 and a previous R01 from NIDDK.