Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2

This study is published in PNAS and details the role the Ace2 and TMPRSS2 in the SARS-CoV-2 infection process and we identified that androgen signaling disruptors have direct antiviral efficacy against SARS-CoV-2 and have potential to treat Covid19.